Vascular complications of chronic pancreatitis and their management: Experience from Children's Hospital, University of child Health Sciences, Lahore, Pakistan

Abstract

Background: Chronic pancreatitis in children is a relatively uncommon but increasingly recognized condition, adversely affecting both exocrine and endocrine pancreatic functions, very rarely can lead to vascular complications. which are clinically significant and require a multidisciplinary approach.

Objective: To determine the frequency, management, and outcomes of vascular complications associated with chronic pancreatitis in children.

Methods: A retrospective study was conducted at the Department of Gastroenterology & Hepatology, Children’s Hospital, University of Child Health Sciences, Lahore, from April 2021 to April 2025. A total of 178 children diagnosed chronic pancreatitis based on INSPPIRE criteria were included in the study. Data were analyzed using SPSS version 25.

Results: Among 178 children (61.7% male, mean age 9.47 ± 3.5 years), vascular complications were identified in 11 (6.2%). The most affected age group was 7-12 years (46.1%). Portal vein thrombosis was the most common complication (6, 54.5%), followed by splenic artery aneurysm and splenic vein thrombosis (2, 18.2% each). Pseudoaneurysm of the gastroduodenal artery, less common and rare also diagnosed (1, 8.3%).

Conclusion: Vascular complications can occur in children with chronic pancreatitis, with portal vein thrombosis being the most common. Early detection and appropriate management are essential to reduce the associated morbidity and mortality.