Hypertrophic Osteoarthropathy: A Case Report

Abstract

Abbreviations:

HOA= hypertrophic osteoarthropathy, PDP= pachydermoperiostosis, ECHO= Echocargiogram, TB=tuberculosis, LFT's= Liver function tests, ALT= alanine transaminase, AST= aspartate transaminase, ESR= erythrocyte sedimentation rate, CT= Computer Tomography, HRCT= High Resolution Computed Tomography, VEGF= Vascular Endothelial Growth Factor

Intrduction:

Hypertrophic Osteoarthropathy (HOA) is characterised by digital clubbing, periosteal new bone formation, polyarthiritis, hyperhidrosis and seborrhea. It has two types, primary HOA (or pachydermoperiostosis) and secondary HOA, the latter involving liver, heart and intestines and commonly predisposing to cancerous diseases like adenocarcinoma of the lung. [1]

Case:

A 7 year old presented with digital clubbing, multiple joint deformities, sweaty palms, with no secondary involvement of organ systems. 

Clinical relevance:

This case is reported because it is a text book case of PDP/ Primary HOA. Whenever in clinical practise, isolated joint involvement with digital clubbing is seen, HOA should be considered as one of the differentials and excluded among other possibilities. 

Laboratory values:

X-ray findings suggestive of periarticular, periosteal reaction over generalised osteopenia. ECHO, HRCT, LFT's and TB screening were all documented as normal.

Reference:

1. DOI: http://doi.org/10.1016/j.jaad.2016.02.226. Hypertrophic osteoarthropathy- a case report.