Severe acute pancreatitis complicating with pancreatic encephalopathy in an adolescent girl

Authors

  • Muhammad Salman Khoso The Department of Pediatric Medicine, Division of Pediatric Gastroenterology, Hepatology & Nutrition, The Children’s Hospital Lahore, University of Child Health Sciences, Lahore, Pakistan
  • ANJUM SAEED The Children's hospital & University of Child Health Sciences, Lahore
  • Zafar Fayyaz The Department of Pediatric Medicine, Division of Pediatric Gastroenterology, Hepatology & Nutrition, The Children’s Hospital Lahore, University of Child Health Sciences, Lahore, Pakistan
  • Amber Goraya The Department of Pediatric Radiology, The Children's Hospital, Lahore
  • Muhammad Nadeem Anjum The Department of Pediatric Medicine, Division of Pediatric Gastroenterology, Hepatology & Nutrition, The Children’s Hospital Lahore, University of Child Health Sciences, Lahore, Pakistan
  • Huma Arshad Cheema The Department of Pediatric Medicine, Division of Pediatric Gastroenterology, Hepatology & Nutrition, The Children’s Hospital & University of Child Health Sciences, Lahore, Pakistan

Keywords:

Acute pancreatitis; Pancreatic encephalopathy; Thiamine; Total parenteral nutrition

Abstract

Pancreatic encephalopathy is a rare and under diagnosed complication of acute pancreatitis due to thiamine (vitamin B1) deficiency resulting from multiple factors. Pancreatic encephalopathy is a neuropsychiatric condition with variable clinical features. In the setting of acute pancreatitis and presents with neurological symptoms. Here, we present the case of a 12-year-old girl admitted with altered sensorium and neurological deficit during acute pancreatitis. She was treated conservatively for severe acute pancreatitis and with vitamin B12 (thiamine) and discharged home with excellent response.

Author Biographies

Muhammad Salman Khoso, The Department of Pediatric Medicine, Division of Pediatric Gastroenterology, Hepatology & Nutrition, The Children’s Hospital Lahore, University of Child Health Sciences, Lahore, Pakistan

Fellow, PEdiatric GI & Hepatology

Zafar Fayyaz, The Department of Pediatric Medicine, Division of Pediatric Gastroenterology, Hepatology & Nutrition, The Children’s Hospital Lahore, University of Child Health Sciences, Lahore, Pakistan

Assoicate Professor

Amber Goraya, The Department of Pediatric Radiology, The Children's Hospital, Lahore

Associate Professor 

Muhammad Nadeem Anjum, The Department of Pediatric Medicine, Division of Pediatric Gastroenterology, Hepatology & Nutrition, The Children’s Hospital Lahore, University of Child Health Sciences, Lahore, Pakistan

Assistant Professor

Huma Arshad Cheema, The Department of Pediatric Medicine, Division of Pediatric Gastroenterology, Hepatology & Nutrition, The Children’s Hospital & University of Child Health Sciences, Lahore, Pakistan

Professor of PEdiatric Gastroenterology, Hepatology 

Published

2023-11-23

Issue

Vol. 47 No. 2 (2023)

Section

Case Report